Vilitra 40 mg (Vardenafil)

Vardenafil 40 mg is a PDE-5 inhibitor that can interact with molecules of many other drugs. If a reaction takes place as such, complexities can occur. The interaction between the medicines could also cancel out the effect of either or both drugs, rendering them useless or harmful to your body. Here is the interaction of Vardenafil 40 mg with other drugs:

• Nitrates (e.g., nitroglycerin): Lowers blood pressure and increases symptoms like dizziness, passing out, and heart issues. Do not take this drug with any nitrates. If using nitrate medicines, consult your doctor before using this drug.
• Alpha-blockers (e.g., tamsulosin): Causes low blood pressure, fainting, and dizziness, especially when standing up quickly. Start with the lowest possible dose of Vardenafil, 40 mg. Be cautious when changing positions (standing or lying down).
• Blood pressure medications: Lowers blood pressure, causing dizziness and fainting. Inform your doctor about blood pressure medications so they can adjust your Vardenafil or blood pressure dose accordingly.
• Ritonavir-containing medications: Increases Levitra 40 mg levels, leading to common side effects like migraines and flushing. If taking Ritonavir, limit the Levitra dose to 2.5 mg within 3 days.
• Antifungals and antibiotics (e.g., ketoconazole, erythromycin): Increases Levitra levels, worsening common side effects. Your doctor will adjust your Levitra dose as needed.
• Cobicistat-containing medications: Increases Vardenafil levels, amplifying overall side effects. Be aware of side effects and inform your doctor. The ED drug dose may be adjusted accordingly.

Avoid Combined Use with Other ED Drugs

It is strictly recommended only to use one ED drug at a time. Even if you want to use a different drug, you have to wait at least 24 hours before doing so. In essence, the combined use of ED drugs should be avoided at all costs. Here's a table that showcases the interaction between Vardenafil 40 mg and other ED drugs:

• Sildenafil (Viagra): Causes blood pressure to drop, leading to severe side effects. Avoid using them together. Wait 24 hours before taking the next dose.
• Tadalafil (Cialis): Causes blood pressure to drop and increases the duration of action (approximately 36 hours), which could be painful and increase the risk of priapism. Avoid using them together. Wait 48 hours or more before using another ED drug.
• Avanafil (Spedra): Causes a quick drop in blood pressure as it is a fast-acting PDE-5 inhibitor. Avoid using them together. Wait 24 hours before another dose.
• Other PDE5 inhibitors: Leads to low blood pressure and an increase in side effects. Avoid using any PDE-5 inhibitor together. Use an ED drug again after 24 hours have passed.

Vilitra 40 mg is a small molecule belonging to the class of PDE-5 inhibitors. They inhibit the action of cGMP ( Cyclic Guanosine Monophosphate). Thus, they help males get and maintain an erection even with sexual dysfunctions like ED. The mechanism of action of Vilitra 40 mg is as follows:

• During sexual stimulation, the Corpuscavernosum produces NO (nitric oxide), which activates the enzyme Guanylate Cyclase (GC).
• In smooth muscle cells of the corpus cavernosum, GC activation raises cGMP production.
• A PDE-5, Vardenafil 40 mg, stops cGMP from degrading, thereby enabling a higher blood flow to the penis and a few hours of the penis is erect.

Though it is a stronger PDE-5 than Sildenafil And Tadalafil, Vardenafil functions much like both.

Although Vilitra 40 mg can be taken with or without food and drinks, some exceptions exist. First of all, only film-coated tablets can be ingested with food and drinks. That aside, here are some common interactions of food and drinks with Vilitra 40 mg:

Generic Levitra 40mg with fatty foods

Generic Levitra 40 mg should not be taken with food items rich in fats. Fatty foods interact with the drug in such a way that they slow down its absorption. Thus, the drug takes effect at least 1 hour later than usual and deters its benefits as well.

Generic Levitra 40mg with alcohol

Alcohol and Levitra 40 mg interaction lowers blood pressure levels in the body. This way, alcohol used with the ED drugs can increase side effects beyond measure. Therefore, combined use of Levitra 40 mg with alcohol should be avoided altogether.

Generic Levitra 40mg with grapefruit juice

Grapefruit juice interacts with liver enzymes. Liver enzymes are one of the key enzymes breaking down Vardenafil. Grapefruit juice makes it difficult for liver enzymes to perform their job. Thus disturbing the benefits of Vardenafil.

Like all medications, Vilitra 40 mg needs to be stored according to instructions as well. Follow these tips to keep your pills as good as new:

• Right temperature: Most ED medicines should be stored in temperature ranges 20°C to 30°C to prevent expiration.
• Away from sunlight: UV rays in sunlight interact with the molecular structure of medicines. That's why they should be kept away from direct sunlight.
• Away from kids and pets: ED medicines should be strictly kept out of reach of children and pets to avoid complicated scenarios.
• Do not freeze or heat up: Freezing or heating the medicine will impact the molecular structure of the medicine rendering it useless. Therefore, do not freeze or heat up ED drugs.
• Do not flush down the toilet: Vardenafil is not on the FDA’s flush list. Thus, it should not be flushed down the drain as it is harmful to the environment.